Protein name:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2;SR Ca(2+)-ATPase 2) ;
Alternative:
Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform ;Calcium pump 2 ;Endoplasmic reticulum class 1/2 Ca(2+) ATPase ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Associated with phospholamban (PLN) (By similarity). Isoform SERCA2B interacts with TRAM2 (via C-terminus). Interacts with HAX1.
Function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Sarcoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MENAHTKTVE | EVLGHFGVNE | STGLSLEQVK | KLKERWGSNE | LPAEEGKTLL |
100:
ELVIEQFEDL | LVRILLLAAC | ISFVLAWFEE | GEETITAFVE | PFVILLILVA |
150:
NAIVGVWQER | NAENAIEALK | EYEPEMGKVY | RQDRKSVQRI | KAKDIVPGDI |
200:
VEIAVGDKVP | ADIRLTSIKS | TTLRVDQSIL | TGESVSVIKH | TDPVPDPRAV |
250:
NQDKKNMLFS | GTNIAAGKAM | GVVVATGVNT | EIGKIRDEMV | ATEQERTPLQ |
300:
QKLDEFGEQL | SKVISLICIA | VWIINIGHFN | DPVHGGSWIR | GAIYYFKIAV |
350:
ALAVAAIPEG | LPAVITTCLA | LGTRRMAKKN | AIVRSLPSVE | TLGCTSVICS |
400:
DKTGTLTTNQ | MSVCRMFILD | KVEGDTCSLN | EFSITGSTYA | PIGEVQKDDK |
450:
PVKCHQYDGL | VELATICALC | NDSALDYNEA | KGVYEKVGEA | TETALTCLVE |
500:
KMNVFDTELK | GLSKIERANA | CNSVIKQLMK | KEFTLEFSRD | RKSMSVYCTP |
550:
NKPSRTSMSK | MFVKGAPEGV | IDRCTHIRVG | STKVPMTPGV | KQKIMSVIRE |
600:
WGSGSDTLRC | LALATHDNPL | KREEMHLEDS | ANFIKYETNL | TFVGCVGMLD |
650:
PPRIEVASSV | KLCRQAGIRV | IMITGDNKGT | AVAICRRIGI | FGQDEDVTSK |
700:
AFTGREFDEL | SPSAQRDACL | NARCFARVEP | SHKSKIVEFL | QSFDEITAMT |
750:
GDGVNDAPAL | KKSEIGIAMG | SGTAVAKTAS | EMVLADDNFS | TIVAAVEEGR |
800:
AIYNNMKQFI | RYLISSNVGE | VVCIFLTAAL | GFPEALIPVQ | LLWVNLVTDG |
850:
LPATALGFNP | PDLDIMNKPP | RNPKEPLISG | WLFFRYLAIG | CYVGAATVGA |
900:
AAWWFIAADG | GPRVSFYQLS | HFLQCKEDNP | DFDGVDCAIF | ESPYPMTMAL |
950:
SVLVTIEMCN | ALNSLSENQS | LLRMPPWENI | WLVGSICLSM | SLHFLILYVE |
1000:
PLPLIFQITP | LNLTQWLMVL | KISLPVILMD | ETLKFVARNY | LEQPGKECVQ |
1044:
PATKSSCSLS | ACTDGISWPF | VLLIMPLVVW | VYSTDTNFSD | MFWS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Pig
Chicken
Rabbit
Rat
Dog
Human
ELISA Kit for Mouse SERCA2
ELISA Kit for Mouse SERCA2
ELISA Kit for Mouse SERCA2
ELISA Kit for Mouse SERCA2
ELISA Kit for Mouse SERCA2
ELISA Kit for Mouse SERCA2
ELISA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
CLIA Kit for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Polyclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
Monoclonal Antibody for Mouse SERCA2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2)
strain :
129/SvJ .
strain :
NIH Swiss .
tissue :
Embryo .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6 .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 604-611 AND 638-655;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
strain :
OF1 .
tissue :
Brain .
tissue :
Hippocampus .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TRAM2
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-143
tissue :
Heart .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-663;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH S100A8 AND S100A9
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-663;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]