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Index > Protein center > Atp2a2(Gene name) > Mouse
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  • Atp2a2 (Gene name),
  • Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Protein name ),  AT2A2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Atp2a2;
    Protein name:
    Sarcoplasmic/endoplasmic reticulum calcium ATPase 2(SERCA2;SR Ca(2+)-ATPase 2);
    Alternative:
    Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform;Calcium pump 2;Endoplasmic reticulum class 1/2 Ca(2+) ATPase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Associated with phospholamban (PLN) (By similarity). Isoform SERCA2B interacts with TRAM2 (via C-terminus). Interacts with HAX1.
    Function:
    This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Sarcoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1044
    Sequence:
    50:
    MENAHTKTVE | EVLGHFGVNE | STGLSLEQVK | KLKERWGSNE | LPAEEGKTLL | 
    100:
    ELVIEQFEDL | LVRILLLAAC | ISFVLAWFEE | GEETITAFVE | PFVILLILVA | 
    150:
    NAIVGVWQER | NAENAIEALK | EYEPEMGKVY | RQDRKSVQRI | KAKDIVPGDI | 
    200:
    VEIAVGDKVP | ADIRLTSIKS | TTLRVDQSIL | TGESVSVIKH | TDPVPDPRAV | 
    250:
    NQDKKNMLFS | GTNIAAGKAM | GVVVATGVNT | EIGKIRDEMV | ATEQERTPLQ | 
    300:
    QKLDEFGEQL | SKVISLICIA | VWIINIGHFN | DPVHGGSWIR | GAIYYFKIAV | 
    350:
    ALAVAAIPEG | LPAVITTCLA | LGTRRMAKKN | AIVRSLPSVE | TLGCTSVICS | 
    400:
    DKTGTLTTNQ | MSVCRMFILD | KVEGDTCSLN | EFSITGSTYA | PIGEVQKDDK | 
    450:
    PVKCHQYDGL | VELATICALC | NDSALDYNEA | KGVYEKVGEA | TETALTCLVE | 
    500:
    KMNVFDTELK | GLSKIERANA | CNSVIKQLMK | KEFTLEFSRD | RKSMSVYCTP | 
    550:
    NKPSRTSMSK | MFVKGAPEGV | IDRCTHIRVG | STKVPMTPGV | KQKIMSVIRE | 
    600:
    WGSGSDTLRC | LALATHDNPL | KREEMHLEDS | ANFIKYETNL | TFVGCVGMLD | 
    650:
    PPRIEVASSV | KLCRQAGIRV | IMITGDNKGT | AVAICRRIGI | FGQDEDVTSK | 
    700:
    AFTGREFDEL | SPSAQRDACL | NARCFARVEP | SHKSKIVEFL | QSFDEITAMT | 
    750:
    GDGVNDAPAL | KKSEIGIAMG | SGTAVAKTAS | EMVLADDNFS | TIVAAVEEGR | 
    800:
    AIYNNMKQFI | RYLISSNVGE | VVCIFLTAAL | GFPEALIPVQ | LLWVNLVTDG | 
    850:
    LPATALGFNP | PDLDIMNKPP | RNPKEPLISG | WLFFRYLAIG | CYVGAATVGA | 
    900:
    AAWWFIAADG | GPRVSFYQLS | HFLQCKEDNP | DFDGVDCAIF | ESPYPMTMAL | 
    950:
    SVLVTIEMCN | ALNSLSENQS | LLRMPPWENI | WLVGSICLSM | SLHFLILYVE | 
    1000:
    PLPLIFQITP | LNLTQWLMVL | KISLPVILMD | ETLKFVARNY | LEQPGKECVQ | 
    1044:
    PATKSSCSLS | ACTDGISWPF | VLLIMPLVVW | VYSTDTNFSD | MFWS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
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    CLIA Kit for Mouse SERCA2
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    CLIA Kit for Mouse SERCA2
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    Polyclonal Antibody for Mouse SERCA2
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    Polyclonal Antibody for Mouse SERCA2
    Polyclonal Antibody for Mouse SERCA2
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    Polyclonal Antibody for Mouse SERCA2
    Polyclonal Antibody for Mouse SERCA2
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    Packing:
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    Polyclonal Antibody for Mouse SERCA2
    Polyclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Monoclonal Antibody for Mouse SERCA2
    Protein for Mouse SERCA2
    Protein for Mouse SERCA2
    Protein for Mouse SERCA2
    Protein for Mouse SERCA2
    Protein for Mouse SERCA2
    Protein for Mouse SERCA2
    Protein for Mouse SERCA2

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    References
    1. 1.
      "Structure and organization of the mouse Atp2a2 gene encoding the sarco(endo)plasmic reticulum Ca(2+)-ATPase 2 (SERCA2) isoforms."
      Ver Heyen M. , Reed T.D. , Blough R.E. , Zilberman A.L. , Loukianov E. , Van Baelen K. , Raeymaekers L. , Periasamy M. , Wutack F.
      Mamm. Genome11:159-163(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2)
      strain: 129/SvJ.
      strain: NIH Swiss.
      tissue: Embryo.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      Lubec G. , Kang S.U. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 604-611 AND 638-655;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      strain: OF1.
      tissue: Brain.
      tissue: Hippocampus.
    4. 4.
      "TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis."
      Stefanovic B. , Stefanovic L. , Schnabl B. , Bataller R. , Brenner D.A.
      Mol. Cell. Biol.24:1758-1768(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAM2
    5. 5.
      "A proteomics approach to identify the ubiquitinated proteins in mouse heart."
      Jeon H.B. , Choi E.S. , Yoon J.H. , Hwang J.H. , Chang J.W. , Lee E.K. , Choi H.W. , Park Z.-Y. , Yoo Y.J.
      Biochem. Biophys. Res. Commun.357:731-736(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-143
      tissue: Heart.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-663;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    7. 7.
      "S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products."
      Boyd J.H. , Kan B. , Roberts H. , Wang Y. , Walley K.R.
      Circ. Res.102:1239-1246(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH S100A8 AND S100A9
    8. 8.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-663;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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